Frontiers | A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System
J Clin Med Res
Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula - ScienceDirect
Brain Sciences | Free Full-Text | Shared Mechanisms of GABAergic and Opioidergic Transmission Regulate Corticolimbic Reward Systems and Cognitive Aspects of Motivational Behaviors
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
Frontiers | Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain
Researchers uncover how kappa opioid receptors drive anxiety
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
Schematic representation of dynorphin/kappa opioid receptor system... | Download Scientific Diagram
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Opioids in cancer: The κ‑opioid receptor (Review)
Development of κ Opioid Receptor Antagonists | Journal of Medicinal Chemistry
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
In major depression, increased kappa and mu opioid receptor levels are associated with immune activation | Acta Neuropsychiatrica | Cambridge Core
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice - ScienceDirect
Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain | Journal of Neuroscience
Opioid receptors: distinct roles in mood disorders | Semantic Scholar
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect
κ-opioid receptor - Wikipedia
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications
